Saturday 23 May 2020

Coronavirus tips: how does coronavirus spread.

What is coronavirus?

 Coronavirus is a large group of viruses that can infect both animals and humans, causing mild respiratory diseases such as pneumonia to mild respiratory diseases such as the common cold.  Rarely, infections spread among people after the animal's coronavirus is infected.  As you may recall from SARS (Severe Acute Respiratory Syndrome) in 2002-2003, this virus was also an example of a coronavirus transmitted from animals to humans.  Another well-known example is the most recent coronavirus strain, MERS (Middle East Respiratory Syndrome), which occurred in the Middle East in 2012 and scientists say the virus was first transmitted from camels to humans.

 It says "Coronavirus" in my test results.  Should I be worried?

 You don't have to worry.  Almost all of the diagnosis of coronavirus is similar to the common cold or flu.  The term 'coronavirus' encompasses the entire family of viruses.  A positive coronavirus test does not mean that you are alert.  It can be very confusing, but if you see the results of using this word, please consult your doctor or medical team.

 How does the coronavirus spread?

 The virus can infect people, usually coughing and sneezing, making personal contact with an infected person, or touching the infected surface and then touching the eyes, nose, and mouth with their hands. According to a reply coronavirus first case was in Wuhan of China and in india coronavirus first case in Delhi.

 How can it help prevent the spread of this disease?

 The Centers for Disease Control and Prevention (CDC) recommends that you follow good hygiene practices, such as washing your hands frequently, getting plenty of fluids, covering your mouth and coughing with a sleeve or tissue, and staying home if you are sick.  Also, even if it doesn't hurt, stay home and practice social distance unless you have to go out (keep at least 6 feet away from others). Some of people and even U. S. Also said that coronavirus start spreading from Wuhan in China. Coronavirus spreading rate is very high. You should have take social distancing.

 What are the symptoms of the new coronavirus (covid-19)?

 The CDC says that the symptoms of the new coronavirus include “fever and lower respiratory illness (eg, cough, shortness of breath) symptoms.” Avoid contact with people suspected of being infected with the virus. Coronavirus also spread through talking. Because some of a report from Japan said that when we talk out micro droplets from mouth spread rapidly.

Can Covid-19 be cured?

 It is a virus that antibiotics do not listen to and there is currently no vaccine.  Due to the lack of specific treatments, medical staff are responding to these symptoms in the usual way and focusing on making the patient more comfortable. So you should always remember all the tips of coronavirus.

 Does CHLA screen patients and visitors?

 Our medical team follows the Los Angeles County Public Health Department's latest guidelines during all interactions with patients to prevent the spread of this new virus.  All hospital staff and visitors are screened orally for symptoms of the disease.  Anyone who has not passed the oral screening test is tested for viruses.  In addition, all CHLA patients are also tested for viruses when hospitalized.  Of course, this includes patients who are about to undergo surgery. Coronavirus effects are very dangerous.

 What signs do you need care?

 If you and your child feel fever, coughing, or shortness of breath, see your doctor right away.  If you suspect corona19, call the hospital or emergency room before your visit.  If you are infected with Corona 19, your health care facility will help you avoid getting infected. Coronavirus disease is very harmful for us.

 Where can I find the most up-to-date information?

 The situation is likely to change as much information and facts about the new virus have been released.  For the most up-to-date information, please download Arogya setu app in your phone.

Friday 22 May 2020

Coronavirus Mutation



RNA viruses, such as Coronavirus , are frequently mutated to easily infect and survive the host. RNA consisting of a single thread is more likely to mutate than double-stranded DNA. It is estimated that there are 26 mutations that a corona19 virus acquires in one year as it multiplies. On the other hand, when the same criteria were applied, an average of 46 mutations occurred in the influenza virus. Coronavirus also has many mutations, but more flu viruses. Why does the virus mutate like this? It is a world of survival. Among the variations are 'similar variation' and 'non-similar variation'. 'Similar mutation' is also called 'silent mutation' because the biological properties of the virus are maintained. On the other hand, 'unlike variation' is completely different to adapt to different environments by changing the biological properties of the virus. 'Non-similar mutations' are all the three-step chain action of base mutation → protein mutation → functional change. Researchers at Beijing University in China divided S-type and L-type based on amino acid mutations in the ORF8 region of corona19 (COVID-19) as of March 12th. It is reported that more L-types have been spread around the world than the original S-type, and on the basis of this, it was estimated that the mutant L-type was more aggressive and highly infectious. However, according to researchers from the University of Cambridge, the Corona 19 is divided into A, B, and C types. A was mainly found in the United States and Australia, B in Asia, and C in Europe.How can we track this variation in Covid-19 worldwide? In the Global Initiative for Sharing All Influenza Data (GISAID), sequencing data from covid-19 patients around the world, including sequencing information from influenza viruses, is uploaded in real time. Scientists around the world actively share the sequencing information of Covid-19, which has been decrypted by countries, and are monitoring the emergence of the strain. Covid-19 data grew rapidly, and as of May 20, 3,25 were registered (provided by Teragene Bio's Tae-Hyung Kim). The Los Alamos National Laboratory in the United States is famous for having developed the world's first nuclear bomb under the Manhattan Project. It is a national research institute under the U.S. Department of Energy, located in New Mexico, which conducts extensive research on national security, space exploration, renewable energy, medicine, nanotechnology, and supercomputers. The medicine part is probably a small part of the lab, but the Los Alamos Department of Theoretical Biology's HIV database team changed what they had to do with a supercomputer to monitor the “GISAID site” after the Corona 19 outbreak. On the 29th of last month, the preprint of the paper was uploaded to the bioRxiv, a repository of international biological journals.


The medicine part is probably a small part of the lab, but the Los Alamos Department of Theoretical Biology's HIV database team changed what they had to do with a supercomputer to monitor the “GISAID site” after the Corona 19 outbreak. On the 29th of last month, the preprint of the paper was uploaded to the bioRxiv, a repository of international biological journals. In the paper titled 'Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2', the highly infectious strain Corona19 virus has been spreading in Europe since the beginning of February, and in the end of March, It has been reported to be the most dominant virus in the world, including Canada. In particular, in the case of the UK, where Corona 19 spread late, almost all of them are 'Spike D614G' mutations.The Los Alamos team first developed a program that tracks SARS-CoV-2 mutations in real time. The team began the joint study to help with vaccine programs developed by scientists at Duke University in the United States and Sheffield University in the United Kingdom. Among them, I focused on Spike (S) -protein. In most vaccine or therapeutic development, the S-protein, which is the first to penetrate human cells, is the most important target. This is because if there are many mutations there, there is a high likelihood that a vaccine or a therapeutic agent being developed may become useless because a “unlike mutation” in which the protein changes to its properties appears. By the time the paper was written, the team found 14 variations that accumulated. The mutation had a geophysical tree over time. Thinking of a tree as a kind of ‘family tree’ is easy to understand. The team looked at each variation as evidence based on the structure of positive selection.World of Survival: Covid-19's mutation is suspicious

The paper noted that the 'D614G' mutation is an urgent concern. This mutation provides a site that can be broken by another serine protease (Elastase) at the S1-S2 junction of the S-protein. As already indicated on the March 13 column, SARS-CoV does not have a self-harmful amino acid site that can act as an enzyme called Purin, which cuts proteins, but is present in the S-protein of SARS-CoV-2. In addition to the purine site, there is one more self-harm of the virus, which quickly cuts and infiltrates and regenerates human cells. This variation began in Europe and spread to new regions, quickly becoming a dominant form. Moreover, due to the high infectivity and lack of existing immunity, there is a high possibility that it will not easily deteriorate even in an environment where the temperature rises and the humidity increases. For viruses, the 'Reproduction Number (R0)', which refers to the average number of people who can infect directly during the period of infection, and the mortality rate during infection are important. Europe is carefully examining whether the 'D614G' is responsible for the relatively high infectious and mortality rates compared to Asia. Why is this mutation suspicious? The 'unlike mutation', such as 'D614G', which also changes the biological properties of the virus, suggests that the evolution of corona19 may occur in human-to-human transmission. First of all, there are warnings that ~ 100 vaccines are currently in development around the world, but if the spread does not calm down this summer, these mutations may be more likely, which could potentially make it difficult to expect vaccines to work. This is because most vaccine developers are developing vaccines based on the viral gene sequence at the beginning of the outbreak. It is necessary to closely monitor the process of mutation, evolution, and adaptation of these viruses, as antigenic drift and accumulation of immunologically related mutations may occur during the period before the first vaccine is delivered. Researchers warn that missing the important evolutionary mutations in these viruses could limit the effectiveness of therapeutics or vaccines. The gene sequence analyzed in the sample also goes on GISAID. Until April 9, 73 gene sequences of domestic patients were analyzed. Fortunately, no meaningful ‘analogous mutations’ such as ‘D614G’ have been found that affect the transmission and pathogenicity of the virus. Couldn't the Korean confirmatory who recently came from the United States or Europe have a ‘D614G’ variation? I am very curious. However, it is not over until the end. No matter how slow it is going back to everyday life, Covid-19 has yet to develop a vaccine or cure. Even when the weather changes to summer, it keeps infectious, and most people don't have antibodies. The only way to prevent re-entrance until the end of Corona 19 is through the regularization of social distances and the active prevention and hygiene of individuals. Corona 19 is also likely to settle for endemic diseases like MERS, colds and flu in the Middle East. Effective eradication vaccines must first be commercialized to eradicate 'naturally occurring'. In addition, natural and intermediate hosts, such as bats and pangolins, must be eradicated and sold for sale in certain regions and markets. The world needs to pay high attention to a strong ban. Otherwise, another new coronavirus would appear through the host in a faster time than Corona19, putting the whole world back into deep pain.


Saturday 16 May 2020

How to get rid of pimples and aches magically.

Unexpected acne is everyones worst nightmare.
Especially just before an event or a special occasion.
Here are some magical tricks to quickly cure an angry pimple or achne to make sure your breakouts wont ruin your day!
Start with half a tsp of turmeric powder which is known to kill bacteria and also aids in healing acne. Add in 1 tsp of cinnamon powder. It has antiseptic and antifungal properties and
reaches deep into your pores to cleanse.

1/2 a tbsp of lemon contains ascorbic acid
to naturally dry out the pimple.

Mix this into a paste with 1 tbsp of honey
to open up clogged pores and add hydration.

Melt 2 tbsp of coconut oil
and add just 2-3 drops of tea tree oil.

Tea tree oil can be harsh and drying on sensitive skin
but when paired with nourishing coconut oil
antifungal coconut oil it
perfectly dries out pimples for a quick fix.

 
Green tea has the power to reduce the redness and puffiness of even the worst spot of acne Remove the tea leaves from a bag of green tea and moisten it with some hot water. When mixed with some cooling aloe vera gel this will calm down those bright red swollen pimples that even concealer cant cover up. Garlic is pretty similar to ingredients like turmeric and cinnamon and tea tree oil.
And is one of those amazing all purpose cures. Mash 2 cloves into a paste and mix it with some rose water to protect your skin from over drying. This mixture may not smell the greatest, but it will help heal your skin! We're sure your grandmom has told you about the superpowers of neem oil. And she isnt wrong. It smoothes your skin while curing acne and helps in scar reduction too. Just mix some with a little bit of honey and dab it on the affected areas to let it work its magic. Baking soda is a natural exfoliant that also neutralises the ph level of the skin to help depuff any swollen areas. Mix 1 tbsp of baking soda with enough water to make a paste and pack it on to the pimple. Just make sure not to rub it into your skin as the granules will end up causing more harm than good.
Powder 1-2 tablets of aspirin This pain relief pill also contains salicylic acid which will dissolve all that gross gunk under your skin to cure your acne. Mix it with a splash of apply cider vinegar for an antibacterial boost and some honey for hydration. Combine the ingredients into a paste and allow it to sit on your skin overnight for a noticeable difference in the morning. Try out any of these life saving recipes to see which gives your skin the best results for an acne free face. Until next time stay tuned and be healthy with smartly.

Wednesday 13 May 2020

How to get rid of blackheads

Who doesn't have at least some blackheads, especially around the nose or the chin?  Blackheads are a common type of acne blemish. This problem is faced by both men and women.
Treatment of skin for removal of blackheads:-
To get rid of blackheads you have to put some work in it. Blackheads are not supposed to be stubborn to treat. Patience and persistence are required to get rid of them. 
First you have to sure that you are doing good skin routine.
Clean every morning and evening and use only oil free products.

Regular exfoliation(removal of dead skin cell)  can be helpful as well, but don't do it over. Excessive dehydration or too often didn't work for your blackheads and it will lead to irritating skin. 
Some of products that helps to remove blackheads are:-

Benzoyl peroxide

 Salicylic acid

 Alpha hydroxy acids

You can also choose to go with a prescription treatment.  Some useful drugs include:

tretinoin

adapalene

adapalene and benzoyl peroxide

tazarotene

It may take several months of consistent treatment before you can see any improvement.
 To jump start the process, you can go to your local day spa or beauty parlour .  The beautician will manually clear, or extract, blockages, and blackheads so you can see some immediate results.

Consistent treatment is critical when dealing with blackheads.  You also need to be realistic about the results.

The informaion for improvement is justified - hoping to have zero blackheads in your face. 

 Also, follicular popularity often makes people believe that they have many blackheads when in fact they do not.  I'm not sure?  

Tuesday 12 May 2020

Symptoms and treatment of covid-19

What are the symptoms of covid-19?


Common symptoms in the early stages include fever, fatigue, dry cough, systemic pain, sore throat, headache, and diarrhea. At this time, when spit is accompanied, it is more likely to be sinusitis(An air-filled cavity in a dense portion of a skull bone) or bronchitis than corona infection. When Virus enter into the lungs 5 to 6 days after infection can cause pneumonia. Symptoms of high fever and shortness of breath appear during pneumonia. The virus level is high in a mild initial stage with a slight throat. Rather, it is highly infectious when the patient does not know whether he or she is infected.

What to do if you suspect infection.
It is difficult to accurately differtiate from symptoms alone. In some cases, it is expressed as enterocolitis( Enterocolitis is an inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon.)symptoms such as diarrhea and abdominal pain without respiratory symptoms. Eventually, a real-time PCR test is required to confirm the diagnosis, but the problem is that respiratory infections and digestion tract infections are very common. Respiratory infections and digestion tract infections are both improved and stable treatments while taking symptom control medication for 2-3 days. Therefore, in reality, it is recommended to take a screening at a screening clinic if there is no improvement or worsening even if you watch while self-contained for 2-3 days.

Rules of life to prevent covid-19.
First, the corona virus is start to fever. For personal hygiene, showering with hot water (flowing water) can be beneficial to your health. Second, be careful with the handles and the surface of objects that can be virus carrier. If you touch a suspected object, wash your hands thoroughly with soap or running water or use an alcohol hand sanitizer. Third, if possible, open the door with your feet without holding the door handle. Wash your hands often, as you often unintentionally rub your eyes and touch your nose to get infected through your hands. Fourth, frequent open mouth cleansing (brushing) can also be prevented.

When will everyday life be possible?
The infectivity is about 2.2 infections in one patient, but it is twice as high considering that there are about 1.2 influenza. It is currently considered that there is a possibility of spreading the community in the metropolitan area, and it is desirable to refrain from gathering events as many as possible, because of the nature of Covid-19, which has strong propagation power, it is expected that many patients will continue to occur in irregular pattern through close contact. Do.

The timing of meetings, events, and openings is difficult to predict, but it seems to be caused mainly by close contact, so it is necessary to wait until the time when the community infection almost disappears. There have been no cases of outdoor activity. Outdoor exercise is fine, but it's a good idea to avoid meeting people or getting in touch during activities.

Is it necessary to wear a mask for the general public?
In the case of active community infection in the case of wearing a mask, it is effective in spreading and preventing infectious diseases, but if there is no community infection or low risk, it is judged that the public does not need to wear it. However, to date, people aged 65 or older, who are known to have a high mortality rate from covid-19, and those suffering from underlying diseases (diabetes, hypertension, kidney disease, cerebrovascular disease, etc.) are used for health care in an enclosed space and a place where many people gather. It is necessary to wear a mask.

The principle is not to reuse health masks. There is no established method to sanetize and dry while preserving the filter function. However, if you don't have or lack a health mask, it is better to wear a cotton mask than not. It is better to dry and reuse in a clean place than not to use.

Saturday 9 May 2020

How to lose belly fat.

6 tips to lose belly fat. 


Abdominal adipose tissue is not only an aesthetic problem, it is a significant risk factor for the development of a number of diseases, especially cardiovascular and type 2 diabetes.

If you are not sure if you have too much fat around your abdomen simply measure your belly circumference: if you are a man and your belly circumference exceeds 102 cm, or a woman with over 88 cm in belly, you are considered a person who has abdominal obesity.
In the following article, we bring you 6 simple and scientifically proven effective ways to get rid of excess fat around the abdomen:

1. Eliminate sugars and sugary drinks from your diet
We all know that sugars are unhealthy. Studies confirm that they have a number of negative effects on human health. All the excess sugar (which the body does not expend for energy production) in the liver is converted into adipose tissue and stored - and studies confirm that this fat is deposited primarily around the abdomen and liver. This in turn leads to insulin resistance and a number of metabolic problems.

The sugars in drinks are even worse - the brain does not register them as hard as solid sugars, but when you start drinking sweet drinks you just want more and more. Studies show that sugary drinks are associated with a 60% increase in the risk of obesity.

Therefore, minimize or completely eliminate sugary drinks from your diet and foods that have added sugars. Read the declarations and you will very quickly learn how to leave on the shelf everything that has unnecessary sugars that harm your health and contribute to weight gain.
2. Increased protein intake contributes to the reduction of adipose tissue in the long run
When it comes to losing extra weight, protein is very important. Studies show that protein reduces the feeling of hunger by 60%, speeds up metabolism by 80-100 calories a day and helps reduce the intake of an average of 441 calories a day. Therefore, anyone aiming to lose extra weight is advised to boost their protein intake.

A study conducted by Loenneke et al. showed that the amount and quality of protein we ingest was inversely related to adipose tissue in the abdominal area. So, if you eat more and better quality protein, you will have a lower risk of accumulating fat in the abdominal area.

Therefore, try to increase the proportion of protein in your diet: eggs, fish, meat, dairy products, legumes and nuts should be a must on your plate. Also, if you find it difficult to get enough protein in your diet, protein supplements are a great solution to supplement your diet and achieve your desired daily protein intake.
3. Reduce your carb intake
Reducing carbohydrate intake is one of the most reliable ways to lose extra pounds. A study conducted by McClernon et al. has shown that reducing carbohydrate intake also reduces the feeling of hunger. Also, 2-3 times higher efficiency of low-carb diet compared to low-fat diet in fat loss has been confirmed.

In addition, low-carb diets have been shown to be extremely effective in losing fat in the abdomen (around the organs), which is extremely dangerous to health, according to Gower and Goss.

Just avoiding refined carbohydrates (sugars, sweets, bread and bakery products) will bring positive results, and if you increase protein intake, the results will be noticeable very quickly.

4. Eat foods rich in fiber
Dietary fiber is most often indigestible, and their consumption is associated with good digestion and weight loss. But when choosing fibers, one should also keep in mind their differences: preference should be given to soluble and viscous fibers, if the goal is to lose extra pounds, according to Chutkan et al.

Namely, these fibers absorb water and form a certain type of gel that "sits" in the intestines. This gel slows down the passage of food through the digestive tract and the absorption of nutrients. The result is a prolonged feeling of satiety and lack of appetite leading to an overall reduced caloric intake, one of the prerequisites for weight loss.

A study conducted by Howarth et al. showed that an increase in daily fiber intake by 14 grams was associated with a 10% reduction in caloric intake and a loss of 2 pounds over a 4-month period.

The best way to increase your dietary fiber intake is to increase your intake of fruits and vegetables. Also, legumes and heavy grains, especially oats, are a good source of fiber. Of the dietary supplements, it is advisable to take glucomannan, which has been proven to contribute to weight loss
5. Exercise is extremely effective in removing belly fat
Regular physical activity is important for several reasons, and among them are better health, lower risk of disease, healthy weight and better appearance. Since there is no training, activity or exercise that can remove fat only from the abdomen or some other critical point, exercise is effective in the overall process of losing weight and reducing the proportion of fat.

No matter what physical activity you do, from walking, running, cycling, aerobics, fitness or some other sports activity, you will increase calorie consumption and thus facilitate weight loss. In addition, physical activity reduces inflammatory processes, regulates blood sugar levels and a number of other metabolic imbalances associated with abdominal adipose tissue.

6. Keep a diet diary to get an insight into what and how much you eat in a day
It is clear to all of us how important it is to eat and drink during the day. But many at the end of the day have no idea how much food they have ingested, whether it is too much or too little, and how much their diet affects their health and appearance.

To get an idea of ​​what your diet really is and whether you are eating something too small or too much, we advise you to keep a diet diary. After only 7 days of keeping a diary, you will be able to gain insight into your diet and make the necessary corrections.

To make it easier for you to measure, use our meal calorie calculator and you will easily get a calculation of whether you eat too much or too little and which nutrients you are missing or have too many.

Friday 8 May 2020

How to lose weight quickly.



You can lose weight healthily by slowly losing weight, and you can keep your slender body for a long time.
However, some experts say, “It’s good to have a slow diet, but there are good ways to lose weight quickly by burning more calories by promoting metabolism.” In this regard, the US portal site Yahoo.com introduced eight ways to lose weight safely and quickly.
◆ Take care of your meals = Skipping a meal does not mean losing weight. When the body feels that the food supply is insufficient, it causes metabolism to slow down to save energy.
Therefore, skipping a meal can have an adverse effect. If you don’t have time to eat, eating nuts or fruits is another way.
◆ Do strength training = Buy a dumbbell or dumbbell that allows you to do strength training once and you will never regret it. Strength training strengthens your muscles and burns more calories.
The more muscle you have, the thinner it is. If you place dumbbells or dumbbells at home or in the office to exercise your muscles, or build up muscles by doing push-ups, squats, lunges, etc. without these equipment, it is also very helpful for your diet.
◆ Drink green tea = According to the study, the group that drank green tea and the group who drank placebo (fake medicine) showed that the group who drank green tea consumed more 70 calories for 24 hours.
It seems that 70 calories a day is low, but if you count it for one year, it is about 3.3kg of fat. An antioxidant called catechin in green tea promotes metabolism.
◆ Avoid calories hidden in drinks = The human body does not recognize calories in liquid foods and liquid calories in the same way. Drinking a large cup of cafe mocha doesn’t feel as full as eating a bowl of pasta.
Because of this, there are cases where you drink two cups of cafe mocha. However, try observing the intake of juice, soda, coffee, wine, etc. a day.
Even if you drink each of these drinks all day long, you’ll get 800 more calories at least until midnight. However, there is still an empty stomach. In particular, alcohol suppresses fat metabolism, making it difficult to burn calories.


Reduce salt intake = Sodium in salt can cause water retention. The retention of water is also known as the retention of body fluids, and refers to a phenomenon in which body organs swell due to abnormal accumulation of water in holes in the body’s circulatory system, tissue, chest cavity, or abdominal cavity.
Sodium’s permissible daily intake is 2400 mg, but most of it exceed this amount. In order to reduce your sodium intake, you should also check the amount of sodium in your snacks, such as soup, canned foods, drinks, chips, and pretzels, as well as salt.
◆ Sleep well enough = If you don’t sleep well or enough, your weight will increase. This is not only because of eating a lot of late night snacks. Studies have shown that women who sleep less than 4 hours a day have slower metabolism than women who sleep for 8 hours.
◆ Drink water frequently = Drinking about 2 liters of water per day is the easiest way to speed up your weight loss. Your body needs water to effectively metabolize the accumulated fat.
Therefore, drinking less water will slow down the metabolic process, making it more difficult to burn calories. Eight glasses of water a day will keep your body running smoothly.
◆ Exercise at night = Exercise can help you lose weight at any time. Particularly, night exercise is more effective at night when the metabolism is gradually slowed down.
Aerobic exercise for about 30 minutes before dinner increases metabolic rate and maintains it for 2-3 hours. Therefore, calories consumed at dinner are not accumulated and consumed well.

Coronavirus tips: how does coronavirus spread.

What is coronavirus?  Coronavirus is a large group of viruses that can infect both animals and humans, causing mild respiratory disease...